Dengue fever, a mosquito-borne viral disease, has established itself in the global epidemic and epidemic transmission cycle. While diagnostic decisions for dengue are often guided by clinical judgment, definitive laboratory testing, including rapid point-of-care testing, has many advantages in the primary care setting. These include providing epidemiological data and diagnostic clarity for atypical cases, and facilitating patient education and compliance. This article discusses the types of dengue diagnostics, when to use them, and the appropriateness of each test. Virus detection diagnostics are usually used within the first week of disease onset, while dengue serology testing is best performed after that time frame. Locally available rapid point-of-care tests,
What is dengue fever?
Dengue fever is an acute disease caused by infection with one or more of four serotypes of dengue virus (DENV 1 to 4). These viruses are transmitted by the female mosquito species Aedes aegypti and, less commonly, Aedes albopictus. It is a dynamic systemic disease with a wide range of clinical manifestations, including severe and non-severe clinical manifestations. Although the disease is usually self-limited, for a minority of patients dengue can lead to life-threatening complications.
In 2009, the World Health Organization (WHO) launched a revised protocol that resulted in a paradigm shift in dengue treatment. The proposed protocol emphasizes early identification of warning signs to optimize triage and management decisions. The following classifications were revised: dengue without warning signs; dengue with warning signs (abdominal pain, persistent vomiting, effusion, mucosal haemorrhage, lethargy, hepatomegaly, increased hematocrit with Dengue with plasma leakage, severe bleeding, or organ failure).
Advantages of Deterministic Testing
Definitive tests for dengue including Easysweet Dengue IgG/IgM And NS1 Combo Rapid Test
allowing early identification and timely notification. They are particularly useful in managing the clinical uncertainty often encountered in primary care. Confirmation will also assist in patient education and encourage compliance with follow-up examinations. Confirmation also allows doctors to better advise patients appropriately, including steps to prevent vector bites, thereby limiting the spread of the disease.